Human Lipolysis-stimulated lipoprotein receptor(LSR) ELISA kit

Code CSB-EL013215HU
Size 96T,5×96T,10×96T
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Product Details

Target Name
lipolysis stimulated lipoprotein receptor
Alternative Names
ILDR3 ELISA Kit; Immunoglobulin like domain containing receptor 3 ELISA Kit; Lipolysis Stimulated Lipoprotein Receptor ELISA Kit; Lipolysis stimulated remnant ELISA Kit; Lipolysis-stimulated lipoprotein receptor ELISA Kit; LISCH ELISA Kit; LISCH protein ELISA Kit; LISCH7 ELISA Kit; Liver specific bHLH Zip transcription factor ELISA Kit; LSR ELISA Kit; LSR_HUMAN ELISA Kit; MGC10659 ELISA Kit; MGC48312 ELISA Kit; MGC48503 ELISA Kit
Uniprot No.
Homo sapiens (Human)
Sample Types
serum, plasma, tissue homogenates
Detection Range
6.25 pg/mL-400 pg/mL
1.56 pg/mL
Assay Time
Sample Volume
Detection Wavelength
450 nm
Research Area
Signal Transduction
Assay Principle
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
To assess the linearity of the assay, samples were spiked with high concentrations of human LSR in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
1:1Average %99
Range %90-103
1:2Average %96
Range %90-99
1:4Average %91
Range %85-95
1:8Average %92
Range %84-97
The recovery of human LSR spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
Sample TypeAverage % RecoveryRange
Serum (n=5) 9383-97
EDTA plasma (n=4)10191-105
Typical Data
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
4002.804 2.722 2.763 2.593
2002.201 2.129 2.165 1.995
1001.470 1.442 1.456 1.286
500.770 0.756 0.763 0.593
250.500 0.512 0.506 0.336
12.50.304 0.300 0.302 0.132
6.250.227 0.235 0.231 0.061
00.168 0.172 0.170
and FAQs
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx

This Human LSR ELISA Kit was designed for the quantitative measurement of Human LSR protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 6.25 pg/mL-400 pg/mL and the sensitivity is 1.56 pg/mL.

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Target Background

(From Uniprot)
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
Gene References into Functions
  1. this study shows that loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in endometrial cancer PMID: 28071680
  2. Lipolysis-stimulated lipoprotein receptor (LSR)-deficient CaCo-2 cells exhibited increased cell proliferation. PMID: 27391068
  3. Results of this study provide novel evidence that tricellular tight junctions protein LSR negatively regulates cancer cell progression and development in endometrial cancer. PMID: 27036040
  4. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1) localized to the bicellular regions. PMID: 28493278
  5. analysis of how Clostridium difficile binary toxin CDT interacts with its host cell receptor, Lipolysis-stimulated Lipoprotein Receptor PMID: 25882847
  6. These data show that Clostridium difficile binary toxin CDT induces clustering of the lipolysis-stimulated lipoprotein receptor into lipid rafts. PMID: 23631918
  7. findings show that Clostridium spiroforme toxin (CST)enters target cells via the lipolysis-stimulated lipoprotein receptor; findings indicate that CST shares LSR with C. difficile CDT and C. perfringens iota toxin as a host cell surface receptor PMID: 22252869
  8. LSR defines tricellular contacts in epithelial cellular sheets by acting as a landmark to recruit tricellulin for tricellular tight junction formation. PMID: 21245199
  9. LISCH7 may have a role in progression of human colon cancer PMID: 17975147

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Subcellular Location
Cell membrane; Single-pass membrane protein.
Protein Families
Immunoglobulin superfamily, LISCH7 family
Database Links

HGNC: 29572

OMIM: 616582

KEGG: hsa:51599

STRING: 9606.ENSP00000354575

UniGene: Hs.466507

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