LSR Antibody

Code CSB-PA801252LA01HU
Size US$166
Order now
  • IHC image of CSB-PA801252LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Immunofluorescence staining of HepG2 cells with CSB-PA801252LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LSR Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
ILDR3 antibody; Immunoglobulin like domain containing receptor 3 antibody; Lipolysis Stimulated Lipoprotein Receptor antibody; Lipolysis stimulated remnant antibody; Lipolysis-stimulated lipoprotein receptor antibody; LISCH antibody; LISCH protein antibody; LISCH7 antibody; Liver specific bHLH Zip transcription factor antibody; LSR antibody; LSR_HUMAN antibody; MGC10659 antibody; MGC48312 antibody; MGC48503 antibody
Raised in
Species Reactivity
Recombinant Human Lipolysis-stimulated lipoprotein receptor protein (112-233AA)
Immunogen Species
Homo sapiens (Human)

The LSR Antibody (Product code: CSB-PA801252LA01HU) is Non-conjugated. For LSR Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA801252LB01HU LSR Antibody, HRP conjugated ELISA
FITC CSB-PA801252LC01HU LSR Antibody, FITC conjugated
Biotin CSB-PA801252LD01HU LSR Antibody, Biotin conjugated ELISA
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
IF 1:50-1:200
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
Gene References into Functions
  1. this study shows that loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in endometrial cancer PMID: 28071680
  2. Lipolysis-stimulated lipoprotein receptor (LSR)-deficient CaCo-2 cells exhibited increased cell proliferation. PMID: 27391068
  3. Results of this study provide novel evidence that tricellular tight junctions protein LSR negatively regulates cancer cell progression and development in endometrial cancer. PMID: 27036040
  4. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1) localized to the bicellular regions. PMID: 28493278
  5. analysis of how Clostridium difficile binary toxin CDT interacts with its host cell receptor, Lipolysis-stimulated Lipoprotein Receptor PMID: 25882847
  6. These data show that Clostridium difficile binary toxin CDT induces clustering of the lipolysis-stimulated lipoprotein receptor into lipid rafts. PMID: 23631918
  7. findings show that Clostridium spiroforme toxin (CST)enters target cells via the lipolysis-stimulated lipoprotein receptor; findings indicate that CST shares LSR with C. difficile CDT and C. perfringens iota toxin as a host cell surface receptor PMID: 22252869
  8. LSR defines tricellular contacts in epithelial cellular sheets by acting as a landmark to recruit tricellulin for tricellular tight junction formation. PMID: 21245199
  9. LISCH7 may have a role in progression of human colon cancer PMID: 17975147

Show More

Hide All

Subcellular Location
Cell membrane; Single-pass membrane protein.
Protein Families
Immunoglobulin superfamily, LISCH7 family
Database Links

HGNC: 29572

OMIM: 616582

KEGG: hsa:51599

STRING: 9606.ENSP00000354575

UniGene: Hs.466507

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details


II. Contact details


III. Ship To


IV. Bill To