Mouse Macrophage mannose receptor 1(MRC1) ELISA kit

1. findings show that TLR6 and mannose receptor participate as macrophage receptors for Mycobacterium lepraemurium PMID: 28317806
2. current study shows that Mrc1-/- mice develop less severe dextran sulfate sodium-induced colitis PMID: 26530135
3. the key roles of the ManR and ASGR in controlling circulating levels of numerous glycoproteins critical for regulating reproductive hormones and blood coagulation. PMID: 27405760
4. PLA2 may prevent inflammatory responses in cisplatin-induced acute kidney injury by modulating Treg cells and IL-10 through the CD206 mannose receptor. PMID: 25993317
5. Hepatic CD206-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection. PMID: 26216935
6. CD206-positive pulmonary macrophages have a critical role in triggering inflammatory cascade during endotoxemic lung inflammation PMID: 25447055
7. These findings suggest that MR plays a major role in Enterococcus faecalis strain EC-12 phagocytosis by the antigen-presenting cells. PMID: 23801521
8. Genetic ablation of the Mrc1 impaired the intracellular collagen degradation pathway. PMID: 24019537
9. Report CD44/macrophage mannose receptor as a ligand/receptor pair involved in the process of lymphocyte transit via the lymphatic vasculature. PMID: 23603511
10. study reports the macrophage response against Leishmania infantum in vivo is characterized by an M2b-like phenotype and C-type lectin receptors signature composed of Dectin-1, mannose receptor (MR)and the DC-SIGN homolog SIGNR3 expression PMID: 23684988
11. These findings suggest that MRC1 plays an important role in the uptake of various bacteria by trophoblast giant cells and may provide an opportunity for those bacteria to escape from phagosomes. PMID: 23163874
12. The results suggest that MRC1 plays a critical role in myeloid plasticity, which in turn affects the adaptive immune response and immunopathogenesis during murine neurocysticercosis. PMID: 23319563
13. CD206 is an pattern recognition receptor in detection of the infective Schistosoma mansoni and modulates IFNgamma production. PMID: 22036898
14. Data show that MR polyubiquitination mediates the recruitment of p97 toward the endosomal membrane, proving the central role of the endocytic receptor and its ubiquitination in antigen translocation. PMID: 21628571
15. The mannose receptor (MR) is the primary receptor mediating the internalization of environmental allergen glycoproteins by dendritic cells. Signals originating from the MR and TLR-2 receptors converge with the notch 1 signalling pathway. PMID: 20819091
16. MR+ macrophages, surrounding early decidual glands, are able to internalize ligands for carbohydrate recognition domain of the receptor, including decidual secretory phase mucin TAG-72. PMID: 15746201
17. macrophage mannose receptor lectin activities are influenced by glycosylation PMID: 15983039
18. These data identify a novel function for mannose receptor (MR) during skeletal muscle growth and suggest that myoblast motility may be a key aspect of regulating myotube growth. PMID: 16864654
19. Study explores Ptgs1 and Mrc1 genes as two new positional candidate genes for allergen-induced airway hyperresponsiveness through comparative sequence analysis and mRNA expression studies of mouse strains with genetically mediated airway responsiveness. PMID: 17454003
20. The role of the mannose receptor in C. neoformans infection in wild-type and knockout mice is reported. PMID: 18391001
21. This study provides a profile of MR N-linked glycosylation that will facilitate our understanding of their physiological role on MR biology in vivo. PMID: 19427834

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KEGG: mmu:17533

STRING: 10090.ENSMUSP00000028045

UniGene: Mm.2019