Interleukin 2 (IL-2) is a cytokine that plays a central role in immune system regulation and T cell activation. Originally discovered as a T cell growth factor, IL-2 is primarily produced by activated CD4+ T helper cells and serves as a key mediator of adaptive immune responses. This cytokine promotes T cell proliferation, differentiation, and survival. It also influences the development and function of regulatory T cells. IL-2 signaling occurs through the IL-2 receptor complex and activates multiple downstream pathways that maintain immune homeostasis and mount effective immune responses against pathogens.
The Pig interleukin 2, IL-2 ELISA Kit (CSB-E06783p) is designed for quantitative measurement of IL-2 in Sus scrofa samples. This sandwich ELISA works with serum, plasma, and tissue homogenates with a detection range of 15.6 pg/mL to 1000 pg/mL and sensitivity of 3.9 pg/mL. The assay requires 50-100 μL sample volume and can be completed within 1-5 hours. Detection is performed at 450 nm wavelength, providing researchers with a reliable tool for studying porcine IL-2 levels in various biological samples.
Application Examples
Note: The following application examples are drawn from a selection of publications citing this product. For additional applications, please refer to the full list of references in the "Citations" section.
This ELISA kit has been used in research examining immune responses and cytokine profiles in porcine models. The applications span studies of inflammatory responses following experimental infections and evaluations of immune system modulation in various physiological contexts.
• Infection studies: Monitoring cytokine responses during experimental viral infections to characterize immune system activation and inflammatory cascades
• Immune profiling: Quantifying cytokine levels in serum samples as part of comprehensive immune response evaluations alongside other inflammatory mediators
• Tissue analysis: Measuring cytokine concentrations in tissue homogenates from liver, spleen, and intestinal mucosa to evaluate local immune responses
• Temporal immune monitoring: Tracking cytokine levels across multiple time points to evaluate the progression and resolution of immune responses
