Recombinant Human Interleukin-22 protein(IL22) (Active)

Code CSB-AP001891HU
Product Type Interleukin
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q9GZX6
Storage Buffer 0.2 μm filtered PBS, pH 5.0 ,lyophilized
Alias IL-22, IL-10-related T-cell-derived-inducible factor, IL-TIF
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.3 ng/ml, corresponding to a specific activity of >3.3x106 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+APISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI
Research Area Immunology
Source E.coli
Gene Names IL22
Expression Region 34-179aa
Tag Info Tag-Free
Mol. Weight 33.6 kDa
Protein Description Full Length of Mature Protein
PubMed ID 10954742; 11197690; 10875937; 12975309; 15489334; 15340161; 11856845; 15983417; 18599299
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Function Cytokine that contributes to the inflammatory response in vivo.
Subcellular Location Secreted
Protein Families IL-10 family
Database Links

HGNC: 14900

OMIM: 605330

KEGG: hsa:50616

STRING: 9606.ENSP00000329384

UniGene: Hs.287369

Pathway Jak-STAT signaling pathway
Th17 cell differentiation

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