CD19 Monoclonal Antibody,FITC Conjugated

Datasheet
Code CSB-MA047662
Product Type Monoclonal Antibody
Size US$258
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol
Immunogen
Raised in Mouse
Species Reactivity Human
Specificity
Tested Applications ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Relevance

 COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate.

* CD19 is a key phenotyping marker of non-T cell leukemia.
 
1.  Nadler, LM et al. (1983) J. Immunol. 131:244
2. Schlossman, SL et al., eds. (1995)  Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York.
3.  Tedder T. et al.  (1994)  Immunol Today. 15:437-442
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Isotype IgG1
Clonality Monoclonal
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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