CD4 Monoclonal Antibody,PE-Cy5 Conjugated

Datasheet
Code CSB-MA570802
Product Type Monoclonal Antibody
Size US$361
Immunogen
Raised in Mouse
Species Reactivity Human
Specificity
Tested Applications ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Relevance

 CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.

CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.
 
1. Ledbetter, J et al.  (1981) J Exp Med  153:310-323.
2. Haynes , B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.
3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.
4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Isotype IgG2b
Clonality Monoclonal
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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