FCGR3A Monoclonal Antibody,PE Conjugated

Code CSB-MA279768
Product Type Monoclonal Antibody
Size US$258
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol
Raised in Mouse
Species Reactivity Human
Tested Applications ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

 COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.

This clone is cross reactive with non-human primate.
1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.
2. Stroncek, D.F., et al. (1991) Blood 77:1572.
3. Wirthmueller, U., et al.  (1992) J. Exp. Med. 175:1381.
4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Isotype IgG1
Clonality Monoclonal
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. COC16
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