NCAM1 Monoclonal Antibody,PE Conjugated

Datasheet
Code CSB-MA208445
Product Type Monoclonal Antibody
Size US$258
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol
Immunogen
Raised in Mouse
Species Reactivity Human
Specificity
Tested Applications ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Relevance
 COC56 reacts with CD56, a 175-220 kDa Neural Cell Adhesion Molecule (NCAM), expressed on 10-25% of peripheral blood lymphocytes, including all CD16+ NK cells and approximately 5% of CD3+ lymphocytes, referred to as NKT cells. It also is present at brain and neuromuscular junctions, certain LGL leukemias, small cell lung carcinomas, neuronally derived tumors, myeloma and myeloid leukemias. CD56 (NCAM) is involved in neuronal homotypic cell adhesion which is implicated in neural development, and in cell differentiation during embryogenesis.
 
1. Knapp, W et al., eds. (1989) Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.
2. Lanier LL . et al. (1991)  J. Immunol. 146:4421-4426.
3. Campbell, JJ et al. (2001) J. Immunol . 166:6477-6482.
4. Cooper MD  et al. (2001)  Trends in Immunol. 22:633-640.
5. Galandrini R  et al. (2002)  Blood. 100:4581-4589.
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Isotype IgG1
Clonality Monoclonal
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. COC56
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