PTPRC Monoclonal Antibody,Purified

Datasheet
Code CSB-MA135182
Product Type Monoclonal Antibody
Size US$258
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol
Immunogen
Raised in Mouse
Species Reactivity Human
Specificity
Tested Applications ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Relevance

 4AA9 reacts with CD45, a 180-220 kDa leukocyte common antigen (LCA). CD45 antigen is expressed at high levels on all hematopoietic cells including T and B lymphocytes, monocytes, granulocytes, NK cells and dendritic cells, but is not expressed on non-hematopoietic cells. CD45 antibody has also been reported to react weakly with mature blood erythrocytes and platelets. CD45 is a protein tyrosine phosphatase receptor that is critically important for T and B cell antigen receptor-mediated activation.

*Target of immunosuppresive antibody treatment.
 
1. Knapp, W et al., eds. (1989)  Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.
2. Trowbridge, IS and Thomas, ML. (1993) Annu. Rev. Immunol. 12:85.
3. Pulido, R et al., (1988) J. Immunol.  140:3851.
4. Roach, T et al., (1997) Curr. Biol. 7:408.
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Isotype IgG2a
Clonality Monoclonal
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 4AA9
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