PTPRC Monoclonal Antibody,PE-Cy5 Conjugated

Datasheet
Code CSB-MA029237
Product Type Monoclonal Antibody
Size US$361
Protocols Flow Cytometry (FC) Protocol
Raised in Mouse
Species Reactivity Human
Tested Applications FC
Relevance  4AA9 reacts with CD45, a 180-220 kDa leukocyte common antigen (LCA). CD45 antigen is expressed at high levels on all hematopoietic cells including T and B lymphocytes, monocytes, granulocytes, NK cells and dendritic cells, but is not expressed on non-hematopoietic cells. CD45 antibody has also been reported to react weakly with mature blood erythrocytes and platelets. CD45 is a protein tyrosine phosphatase receptor that is critically important for T and B cell antigen receptor-mediated activation.*Target of immunosuppresive antibody treatment. 1. Knapp, W et al., eds. (1989)  Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Trowbridge, IS and Thomas, ML. (1993) Annu. Rev. Immunol. 12:85.3. Pulido, R et al., (1988) J. Immunol.  140:3851.4. Roach, T et al., (1997) Curr. Biol. 7:408.
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Isotype IgG2a
Clonality Monoclonal
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 4AA9
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