Human Transferrin protein

Code CSB-NP002501h
Product Type Native Protein
Size US$1600
Relevance Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Form Liquid
Storage Buffer PBS, pH 7.4
Alias Serotransferrin,Beta-1 metal-binding globulin,Siderophilin
Biological_Activity Not test
Purity >95% (SDS-PAGE)
Sequence Full length protein
Research Area Cardiovascular
Source Purified from Human plasma
Protein Names Human Transferrin protein
Storage Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
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