Your Good Partner in Biology Research
Tel : 301-363-4651
Your Good Partner in Biology Research
| Code | CSB-NP005201Rb |
| Product Type | Native Protein |
| Size |
US$250Purchase it in Cusabio online store (only available for customers from the US) |
| Relevance | The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2, 6 linked sialic acid residues. The other part of an antibody, called the Fab region, contains variable sections that define the specific target that the antibody can bind. By contrast, the Fc region of all antibodies in a class are the same for each species; they are constant rather than variable. The Fc region is, therefore, sometimes incorrectly termed the "fragment constant region". |
| Image |
|
| Tested Applications | ELISA, WB, SDS-PAGE |
| Form | Liquid |
| Storage Buffer | PBS, pH 7.4 |
| Alias | Fragment crystallizable region |
| Biological_Activity | Not test |
| Purity | >95% (SDS-PAGE) |
| Sequence | Full length protein |
| Research Area | Immunology |
| Source | Rabbit serum IgG |
| Protein Names | Rabbit IgG Fc fragment |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
Recombinant Human Ribonucleoside-diphosphate reductase large subunit(RRM1)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain(CD8A),partial
Express system: Yeast
Species: Bos taurus (Bovine)
Recombinant Human Alanine aminotransferase 1(GPT)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Peroxisomal multifunctional enzyme type 2(HSD17B4)
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Transcription activator BRG1(SMARCA4),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Rabbit Tropomyosin alpha-1 chain(TPM1)
Express system: Yeast
Species: Oryctolagus cuniculus (Rabbit)
Recombinant Human Nuclear transport factor 2(NUTF2)
Express system: E.coli
Species: Homo sapiens (Human)
Wait!
Join the 20,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.
Sign up now to get your $50 coupon for protein expression service!
We don't deal in spam.
