Streptolysin O protein

Code CSB-NP078041Ba
Product Type Native Protein
Size US$173335
Relevance Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Form Liquid
Storage Buffer PBS, pH 7.4
Alias SLO
Biological_Activity Not test
Purity >95% (SDS-PAGE)
Sequence Full length protein
Research Area Microbiology
Source Purified from Streptococcus hemolyticus
Protein Names Streptolysin O protein
Storage Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
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