AATK Antibody

Code CSB-PA046504
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA046504(AATK Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA046504(AATK Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
AATK
Alternative Names
AATK antibody; AATYK antibody; AATYK1 antibody; Apoptosis associated tyrosine kinase antibody; Apoptosis-associated tyrosine kinase antibody; Brain apoptosis associated tyrosine kinase antibody; Brain apoptosis-associated tyrosine kinase antibody; CDK5 binding protein antibody; CDK5-binding protein antibody; KIAA0641 antibody; Lemur tyrosine kinase 1 antibody; LMR1 antibody; LMTK1 antibody; LMTK1_HUMAN antibody; p35 binding protein antibody; p35-binding protein antibody; p35BP antibody; Serine/threonine protein kinase LMTK1 antibody; Serine/threonine-protein kinase LMTK1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human AATK
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May be involved in neuronal differentiation.
Gene References into Functions
  1. ATKK was validated as a target gene of miR-558, and upregulation of miR-558 was observed in radioresistant lung cancer cells. Additionally, ectopic overexpression of ATKK partially but significantly reduced the miR-558-induced radioresistance. PMID: 27485693
  2. Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. PMID: 14521924
  3. This paper deals with the mouse ortholog. PMID: 17651901
Subcellular Location
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear.
Protein Families
Protein kinase superfamily, Tyr protein kinase family
Tissue Specificity
Expressed in brain.
Database Links

HGNC: 21

OMIM: 605276

KEGG: hsa:9625

STRING: 9606.ENSP00000324196

UniGene: Hs.514575

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