ABCG8 Antibody

Datasheet
Code CSB-PA875651LA01HU
See More Details
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q9H221
Image
  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA875651LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA875651LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Western Blot
    Positive WB detected in: Mouse heart tissue, Mouse lung tissue, Mouse kidney tissue, Mouse stomach tissue
    All lanes: ABCG8 antibody at 2.8μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 76 kDa
    Observed band size: 76 kDa

Immunogen Recombinant Human ATP-binding cassette sub-family G member 8 protein (176-413AA)
Raised in Rabbit
Species Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF; Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200
Relevance Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias ATP-binding cassette sub-family G member 8 (Sterolin-2), ABCG8
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Research Area Cardiovascular
Target Names ABCG8
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile
Involvement in disease Gallbladder disease 4 (GBD4); Sitosterolemia (STSL)
Subcellular Location Cell membrane, Multi-pass membrane protein, Apical cell membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCG family, Eye pigment precursor importer (TC 3.A.1.204) subfamily
Tissue Specificity Predominantly expressed in the liver (PubMed:11099417, PubMed:11452359). Low expression levels in the small intestine and colon (PubMed:11099417). Very low levels in other tissues, including brain, heart and spleen (PubMed:11452359).
Database Links

HGNC: 13887

OMIM: 210250

KEGG: hsa:64241

STRING: 9606.ENSP00000272286

UniGene: Hs.413931

Pathway Cholesterol metabolism

Related Products

ABCG8 Antibodies

ABCG8 Antibodies for Homo sapiens (Human)

ABCG8 Antibodies for Human

ABCG8 Proteins

ABCG8 Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.