ABHD4 Antibody

Code CSB-PA901885
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human brain tissue using ABHD4 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ABHD4 Polyclonal antibody
Uniprot No.
Target Names
ABHD4
Alternative Names
ABHD4(Lyso)-N-acylphosphatidylethanolamine lipase antibody; EC 3.1.1.- antibody; Alpha/beta hydrolase domain-containing protein 4 antibody; Abhydrolase domain-containing protein 4 antibody; Alpha/beta-hydrolase 4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human ABHD4.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
Gene References into Functions
  1. ABHD4 is a novel genetic regulator of anoikis sensitivity. PMID: 22488300
  2. Lysophospholipase/phospholipase B (EC 3.1.1.5) specific for N-acyl phosphatidylethanolamine (NAPE) suggesting a role in the biosynthesis of N-acyl ethanolamines including the endocannabinoid anandamide. PMID: 16818490
Protein Families
Peptidase S33 family, ABHD4/ABHD5 subfamily
Database Links

HGNC: 20154

KEGG: hsa:63874

STRING: 9606.ENSP00000414558

UniGene: Hs.445665

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