ACOT11 Antibody

Code CSB-PA001164GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ACOT11
Alternative Names
ACO11_HUMAN antibody; ACOT 11 antibody; ACOT11 antibody; Acyl CoA thioester hydrolase 11 antibody; Acyl CoA thioesterase 11 antibody; Acyl coenzyme A thioesterase 11 antibody; Acyl-CoA thioester hydrolase 11 antibody; Acyl-CoA thioesterase 11 antibody; Acyl-coenzyme A thioesterase 11 antibody; Adipose associated thioesterase antibody; Adipose-associated thioesterase antibody; BFIT 1 antibody; BFIT 2 antibody; BFIT antibody; BFIT1 antibody; BFIT2 antibody; Brown fat inducible thioesterase antibody; Brown fat-inducible thioesterase antibody; KIAA0707 antibody; OTTHUMP00000046722 antibody; StAR related lipid transfer (START) domain containing 14 antibody; STARD 14 antibody; STARD14 antibody; START domain containing 14 antibody; THEA antibody; THEM 1 antibody; THEM1 antibody; Thioesterase adipose associated antibody; Thioesterase superfamily member 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ACOT11
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
Gene References into Functions
  1. The N-terminal region of human fat inducible thioesterase variant 2 constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage. PMID: 22897136
  2. BFIT supports the transition of thermogenic brown adipose tissue towards increased metabolic activity, probably through alteration of intracellular fatty acyl-CoA concentration. PMID: 11696000
Subcellular Location
Mitochondrion matrix. Cytoplasm.
Tissue Specificity
Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
Database Links

HGNC: 18156

OMIM: 606803

KEGG: hsa:26027

STRING: 9606.ENSP00000360366

UniGene: Hs.745173

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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