ADAL Antibody, Biotin conjugated

Code CSB-PA724932LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ADAL Polyclonal antibody
Uniprot No.
Target Names
ADAL
Alternative Names
ADAL antibody; ADAL1 antibody; Adenosine deaminase-like protein antibody; EC 3.5.4.- antibody; Adenosine deaminase-like protein isoform 1 antibody; N6-mAMP deaminase antibody; HsMAPDA antibody; N6-methyl-AMP aminohydrolase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Adenosine deaminase-like protein (1-267AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro.
Gene References into Functions
  1. Mutations in adenosine deaminase-like (ADAL) protein confer drug resistance in Uterine Cervical Neoplasms. PMID: 23645737
  2. Data indicated that ADAL1 specifically acts at the 6-position of purine and 2-aminopurine nucleoside monophosphates. PMID: 21755941
Protein Families
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
Database Links

HGNC: 31853

KEGG: hsa:161823

UniGene: Hs.533913

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