ADAM2 Antibody

Datasheet

Code	CSB-PA236720
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA236720(ADAM2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA236720(ADAM2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, hela cells, Primary antibody: CSB-PA236720(ADAM2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q99965

Target Names

ADAM2

Alternative Names

A disintegrin and metalloproteinase domain 2 antibody; ADAM 2 antibody; ADAM metallopeptidase domain 2 antibody; Adam2 antibody; ADAM2_HUMAN antibody; AI323749 antibody; Cancer/testis antigen 15 antibody; CRYN1 antibody; CRYN2 antibody; CT15 antibody; Disintegrin and metalloproteinase domain-containing protein 2 antibody; Fertilin beta antibody; Fertilin subunit beta antibody; Ftnb antibody; PH 30 antibody; PH 30b antibody; PH-30 antibody; PH30 antibody; Ph30 beta antibody; PH30-beta antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human ADAM2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

Gene References into Functions

ADAM2, CALR3 and SAGE1 cancer/testis antigens are not promising targets for immunotherapy of breast and lung cancer. PMID: 26252478
The fertilin beta contributes not only to successful fertilization, but may has an important impact in development of preimplantation embryos. PMID: 18292840

Subcellular Location

Membrane; Single-pass type I membrane protein.

Tissue Specificity

Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.

Database Links

HGNC: 198

OMIM: 601533

KEGG: hsa:2515

STRING: 9606.ENSP00000265708

UniGene: Hs.177959

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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