ADAMTS6 Antibody

Datasheet

Code	CSB-PA657730
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA657730(ADAMTS6 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA657730(ADAMTS6 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9UKP5

Target Names

ADAMTS6

Alternative Names

ADAMTS6 antibody; A disintegrin and metalloproteinase with thrombospondin motifs 6 antibody; ADAM-TS 6 antibody; ADAM-TS6 antibody; ADAMTS-6 antibody; EC 3.4.24.- antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human ADAMTS6

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:5000
IHC	1:15-1:50

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. PMID: 30012220
High ADAMTS-6 expression is a marker of poor prognosis in patients with esophageal squamous cell carcinoma. PMID: 29475036
Using siRNA, over-expression and mutagenesis, it was found ADAMTS6 inhibits and ADAMTS10 is required for focal adhesions, epithelial cell-cell junction formation, and microfibril deposition. PMID: 27779234
ADAMTS6 inhibits breast tumor development by regulating the ERK pathway via binding of miR-221-3p PMID: 27542224
Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
Study shows that the ADAMTS6 transcript contains unusually large untranslated regions (UTRs) at both the 5' and 3'end, and the 5'UTR contains 11 AUG codons upstream of the predicted ADAMTS6 start codon. PMID: 16129570
The gain of function studies indicated that ADAM metallopeptidase with thrombospondin type 1 motif 6 activate NR5A1 gene expression. PMID: 18579725

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Subcellular Location

Secreted, extracellular space, extracellular matrix.

Tissue Specificity

Expressed at low levels in placenta and barely detectable in a number of other tissues.

Database Links

HGNC: 222

OMIM: 605008

KEGG: hsa:11174

STRING: 9606.ENSP00000370443

UniGene: Hs.482291

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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