AGAP1 Antibody

Code CSB-PA780863
Size US$166
Order now
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA780863(AGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA780863(AGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, hela cells, mouse lung tissue, Primary antibody: CSB-PA780863(AGAP1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
Alternative Names
AGAP 1 antibody; AGAP-1 antibody; Agap1 antibody; AGAP1_HUMAN antibody; Arf GAP with GTP binding proteinlike ANK repeat and PH domains 1 antibody; Arf-GAP with GTPase; ANK repeat and PH domain-containing protein 1 antibody; ArfGAP with GTPase domain ankyrin repeat and PH domain 1 antibody; Centaurin gamma 2 antibody; Centaurin-gamma-2 antibody; CENTG2 antibody; Cnt-g2 antibody; GGAP 1 antibody; GGAP1 antibody; GTP binding and GTPase activating protein 1 antibody; GTP-binding and GTPase-activating protein 1 antibody; KIAA1099 antibody; MGC71657 antibody
Raised in
Species Reactivity
Synthetic peptide of Human AGAP1
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen affinity purification
It differs from different batches. Please contact us to confirm it.
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Tested Applications
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.
Gene References into Functions
  1. The effect of AGAP1 Knockdown could be rescued by FLAG-AGAP1, but not by an AGAP1 mutant that did not bind Kif2A efficiently, ArfGAP1-HA or Kif2A-GFP. The results support the hypothesis that the Kif2A.AGAP1 complex contributes to control of cytoskeleton remodeling involved in cell movement. PMID: 27531749
  2. GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity. PMID: 22453919
  3. overexpression inhibited formation of platelet-derived growth factor-induced ruffles and also induced loss of actin stress fibers PMID: 12388557
  4. AGAP1 is a novel binding partner of nitric oxide-sensitive guanylyl cyclase PMID: 15381706
  5. CENTG2 is an intriguing candidate gene that merits further scrutiny for its role in autism. PMID: 15892143
  6. The AGAP1 has been found to associate with the adaptor protein complex AP-3 and regulate the function of AP-3 endosomes. PMID: 16079295
  7. AGAP1 is unique among the AZAPs in its specificity for Arf1, and this activity is dependent on its NH(2)-terminal GTPase-like domain. AGAP1 induce reciprocal activation of Arf6. PMID: 18003747

Show More

Hide All

Subcellular Location
Cytoplasm. Note=Associates with the endocytic compartment.
Protein Families
Centaurin gamma-like family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 16922

OMIM: 608651

KEGG: hsa:116987

STRING: 9606.ENSP00000307634

UniGene: Hs.435039

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details


II. Contact details


III. Ship To


IV. Bill To