AMPD3 Antibody

Code CSB-PA008865
Size US$100
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Product Details

Uniprot No.
Target Names
AMPD3
Alternative Names
Adenosine monophosphate deaminase (isoform E) antibody; Adenosine monophosphate deaminase 3 antibody; AMP aminohydrolase antibody; AMP deaminase 3 antibody; AMP deaminase isoform E antibody; Ampd3 antibody; AMPD3_HUMAN antibody; Erythrocyte AMP deaminase antibody; Erythrocyte specific AMP deaminase antibody; Erythrocyte specific protein antibody; Erythrocyte type AMP deaminase antibody; Erythroid Marker antibody; Myoadenylate deaminase antibody; OTTHUMP00000230743 antibody; OTTHUMP00000230746 antibody; OTTHUMP00000230747 antibody; OTTHUMP00000230748 antibody; OTTHUMP00000230749 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human AMPD3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
AMP deaminase plays a critical role in energy metabolism.
Gene References into Functions
  1. N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding PMID: 12213808
  2. mtDNA deletion coordinately induces AMP deaminase to contribute to the loss of atrial adenine nucleotides through degrading AMP excessively. PMID: 12604357
  3. The primary underlying mechanism for increased catabolic flow through the AMP deaminase reaction in circulating erythrocytes of individuals with familial phosphofructokinase deficiency is Ca2+-calmodulin activation of AMP deaminase isoform E. PMID: 16670071
Involvement in disease
Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)
Protein Families
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
Database Links

HGNC: 470

OMIM: 102772

KEGG: hsa:272

STRING: 9606.ENSP00000379802

UniGene: Hs.501890

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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