AP1S1 Antibody

Code CSB-PA001866LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) AP1S1 Polyclonal antibody
Uniprot No.
Target Names
AP1S1
Alternative Names
Adapter related protein complex 1 sigma 1A subunit antibody; Adapter-related protein complex 1 sigma-1A subunit antibody; Adaptor protein complex AP-1 sigma-1A subunit antibody; Adaptor protein complex AP1 sigma 1A subunit antibody; AP-1 complex subunit sigma-1A antibody; AP1 complex subunit sigma 1A antibody; AP19 antibody; AP1S1 antibody; AP1S1_HUMAN antibody; CLAPS1 antibody; Clathrin assembly protein complex 1 sigma 1A small chain antibody; Clathrin assembly protein complex 1 sigma-1A small chain antibody; Clathrin coat assembly protein AP19 antibody; Golgi adaptor HA1/AP1 adaptin sigma 1A subunit antibody; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit antibody; HA1 19 kDa subunit antibody; Sigma 1a subunit of AP-1 clathrin antibody; Sigma 1a subunit of AP1 clathrin antibody; Sigma adaptin 1A antibody; Sigma-adaptin 1A antibody; Sigma1A adaptin antibody; Sigma1A-adaptin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human AP-1 complex subunit sigma-1A protein (1-127AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The AP1S1 Antibody (Product code: CSB-PA001866LA01HU) is Non-conjugated. For AP1S1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA001866LB01HU AP1S1 Antibody, HRP conjugated ELISA
FITC CSB-PA001866LC01HU AP1S1 Antibody, FITC conjugated
Biotin CSB-PA001866LD01HU AP1S1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Gene References into Functions
  1. We solved the pathogenetic mechanism of MEDNIK syndrome, demonstrating that AP1S1 regulates intracellular copper machinery mediated by copper-pump proteins PMID: 23423674
  2. A splice mutation in AP1S1 was found in four families with a neurocutaneous syndrome. PMID: 19057675
  3. Isolation and description of the rat and mouse genes. PMID: 2040623
Involvement in disease
Mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, and keratoderma (MEDNIK)
Subcellular Location
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein Families
Adaptor complexes small subunit family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 559

OMIM: 603531

KEGG: hsa:1174

STRING: 9606.ENSP00000336666

UniGene: Hs.489365

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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