ARHGAP20 Antibody

Code CSB-PA002021GA01HU
Size US$685
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Product Details

Uniprot No. Q9P2F6
Target Names ARHGAP20
Alternative Names ARHGAP20 antibody; KIAA1391 antibody; Rho GTPase-activating protein 20 antibody; Rho-type GTPase-activating protein 20 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ARHGAP20
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Gene References into Functions
  1. The similar expression profiles of ARHGAP20 in 13q14 and 11q22-23 deleted CLL cases suggest a molecular connection and an intriguing mechanism of regulation PMID: 21500311
  2. human KIAA1391 gene and mouse Kiaa1391 gene encode RhoGAP proteins with RA domain and two ANXL repeats PMID: 14532992
  3. RA-RhoGAP transduces a signal from Rap1 to Rho and regulates the neurite outgrowth PMID: 16014623
Involvement in disease A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL) (PubMed:15543602). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes (PubMed:15543602).
Tissue Specificity Expressed predominantly in the brain. Lower expression is found in lymph nodes.
Database Links

HGNC: 18357

OMIM: 609568

KEGG: hsa:57569

STRING: 9606.ENSP00000260283

UniGene: Hs.6136

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