ARHGEF10 Antibody

Datasheet

Code	CSB-PA176345
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA176345(ARHGEF10 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA176345(ARHGEF10 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O15013

Target Names

ARHGEF10

Alternative Names

ARHGA_HUMAN antibody; ARHGEF10 antibody; DKFZp686H0726 antibody; GEF10 antibody; KIAA0294 antibody; MGC131664 antibody; Rho guanine nucleotide exchange factor (GEF) 10 antibody; Rho guanine nucleotide exchange factor 10 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human ARHGEF10

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May play a role in developmental myelination of peripheral nerves.

Gene References into Functions

Ectopic expression of an N-terminal-truncated ARHGEF10 mutant led to the generation of large vesicle-like structures containing both Rab6 and Rab8. PMID: 27550519
This study provided new insights into the roles of ARHGEF10 SNPs rs2280887, rs9657362, and rs4480162 in the development and progression of ischemic stroke in northern Chinese Han population. PMID: 27934548
A significant association of ARHGEF10 with paclitaxel chemotherapy induced peripheral neuropathy was found. PMID: 26143528
Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10). PMID: 21719701
the rs4376531 polymorphism in the ARHGEF10 gene is a risk factor for atherothrombotic stroke in the Han Chinese population PMID: 21743172
The functional single-nucleotide polymorphism of ARHGEF10 confers the susceptibility to atherothrombotic stroke. PMID: 20042462
data support a role for ARHGEF10 in developmental myelination of peripheral nerves PMID: 14508709
Gef10 is the third member of a Rho-specific GEF family with unusual protein architecture PMID: 16896804
A novel RhoA-dependent signaling pathway under the control of ARHGEF10 has a pivotal role in the regulation of the cell division cycle. PMID: 19635168

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Involvement in disease

Slowed nerve conduction velocity (SNCV)

Database Links

HGNC: 14103

OMIM: 608136

KEGG: hsa:9639

STRING: 9606.ENSP00000340297

UniGene: Hs.98594

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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