ASIC5 Antibody

Code CSB-PA865174ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA865174ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA865174ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ASIC5 Polyclonal antibody
Uniprot No.
Target Names
ASIC5
Alternative Names
Acid-sensing ion channel 5 antibody; amiloride sensitive cation channel 5, intestinal antibody; Amiloride sensitive sodium channel antibody; Amiloride-sensitive cation channel 5 antibody; ASIC5 antibody; ASIC5_HUMAN antibody; HINaC antibody; Human intestine Na(+) channel antibody; INAC antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acid-sensing ion channel 5 protein (140-330AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.
Gene References into Functions
  1. hBASIC shares further key features with its rat ortholog: it is blocked by extracellular divalent cations, is inhibited by micromolar concentrations of the diarylamidine diminazene, and activated by millimolar concentrations of flufenamic acid. PMID: 23842738
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC5 subfamily
Tissue Specificity
Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.
Database Links

HGNC: 17537

OMIM: 616693

KEGG: hsa:51802

STRING: 9606.ENSP00000442477

UniGene: Hs.381349

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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