B3GNT2 Antibody

Datasheet

Code	CSB-PA002500LA01HU
Size	US$166
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Image	Western blot All lanes: B3GNT2 antibody at 4µg/ml Lane 1: 293T whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47, 46 kDa Observed band size: 47 kDa Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA002500LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) B3GNT2 Polyclonal antibody

Uniprot No.

Q9NY97

Target Names

B3GNT2

Alternative Names

3-galactosyltransferase 7 antibody; 3-GalTase 7 antibody; 3-Gn-T1 antibody; 3-Gn-T2 antibody; 3-N-acetylglucosaminyltransferase 1 antibody; 3-N-acetylglucosaminyltransferase 2 antibody; b3Gal-T7 antibody; B3GN2_HUMAN antibody; B3GNT antibody; B3GNT2 antibody; Beta 1 3 galactosyltransferase 7 antibody; Beta-1 antibody; Beta-3-Gx-T7 antibody; Beta3Gal-T7 antibody; Beta3GalT7 antibody; Beta3Gn T1 antibody; Beta3Gn-T1 antibody; Beta3Gn-T2 antibody; Beta3GNT antibody; BGnT-1 antibody; BGnT-2 antibody; UDP-Gal:beta-GlcNAc beta-1 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1 antibody; UDP-GlcNAc:betaGal beta-1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 protein (29-397AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The B3GNT2 Antibody (Product code: CSB-PA002500LA01HU) is Non-conjugated. For B3GNT2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA002500LB01HU	B3GNT2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA002500LC01HU	B3GNT2 Antibody, FITC conjugated
Biotin	CSB-PA002500LD01HU	B3GNT2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors. Probably constitutes the main polylactosamine synthase.

Gene References into Functions

we confirmed the involvement of BGNT-1.1 in ciliated sensory neuron function and morphogenesis. BGNT-1.1 functions at the trans-Golgi network of sheath cells (glia) to influence dye-filling and cilium length, in a cell non-autonomous manner. Notably, BGNT-1.1 is the orthologue of human B3GNT1/B4GAT1, a glycosyltransferase associated with Walker-Warburg syndrome (WWS). PMID: 27508411
High B3GNT2 expression is associated with hepatocellular carcinoma. PMID: 25605193
data reveals beta3GnT2 and polyLacNAc may be involved in the progression of the pre-malignant lesions of human the uterine cervix. PMID: 24998922
beta3Gal-T5, controlled by the intestinal homeoproteins, may play an important role in the specific function of intestinal cells by modifying the carbohydrate structure of glycoproteins PMID: 12855703
beta3Gal-T5 is presumed to be responsible for the synthesis of CA 19-9 in pancreatic cancer tissue. PMID: 14555842
beta 3Gal-T5 plays a relevant role in gastrointestinal and pancreatic tissues counteracting the glycosylation pattern associated with malignancy PMID: 14686931
beta1, 3-N-acetylglucosaminyltransferase is similar to a new protein, beta3-GnTL1 PMID: 15560372
up-regulation of beta3Gn-T8 in differentiated cells increases poly-N-acetyllactosamine chains by activating intrinsic beta3Gn-T2. PMID: 18826941

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Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.

Protein Families

Glycosyltransferase 31 family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 15629

OMIM: 605581

KEGG: hsa:10678

STRING: 9606.ENSP00000305595

UniGene: Hs.173203

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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