BAI3 Antibody

Code CSB-PA040099
Size US$167 How to order?
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Product Details

Uniprot No. O60242
Target Names ADGRB3
Alternative Names BAI3 antibody; BAI3_HUMAN antibody; Brain-specific angiogenesis inhibitor 3 antibody; dJ91B17.1 (brain specific angiogenesis inhibitor 3) antibody; KIAA0550 antibody
Raised in Rabbit
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from the N-terminal region of Human BAI-3.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Protocols Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1.
Gene References into Functions
  1. BAI3 has the potential to act as target for pharmaceutical intervention inline with developing trends in molecular pathology aiming to provide personalized, treatment regimes based on tumor-specific mutation profiles. PMID: 28537194
  2. Discriminated small-cell lung carcinoma from large-cell neuroendocrine lung carcinoma with immunohistochemical markers BAI3, CDX2 and VIL1. PMID: 24266897
  3. The BAI3 locus where the rs9363864 maps is a new candidate for venous thromboembolism risk PMID: 20946148
  4. C1ql proteins are secreted signaling molecules that bind to BAI3 and act, at least in part, to regulate synapse formation and/or maintenance. PMID: 21262840
  5. Level of disorganized symptoms was significantly (P < 6.00 x 10(-5)) associated 2 SNPs within the brain-specific angiogenesis inhibitor 3 (BAI3) gene, which is highly expressed in brain during development. PMID: 18628273

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Subcellular Location Cell membrane; Multi-pass membrane protein.
Protein Families G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines.
Database Links

HGNC: 945

OMIM: 602684

KEGG: hsa:577

STRING: 9606.ENSP00000359630

UniGene: Hs.13261

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Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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