BAIAP3 Antibody

Datasheet

Code	CSB-PA002547LA01HU
Size	US$166
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Image	IHC image of CSB-PA002547LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. IHC image of CSB-PA002547LA01HU diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) BAIAP3 Polyclonal antibody

Uniprot No.

O94812

Target Names

BAIAP3

Alternative Names

BAI1 associated protein 3 antibody; BAI1-associated protein 3 antibody; Baiap3 antibody; BAIP3_HUMAN antibody; BAP2 antibody; BAP3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human BAI1-associated protein 3 protein (131-257AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The BAIAP3 Antibody (Product code: CSB-PA002547LA01HU) is Non-conjugated. For BAIAP3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA002547LB01HU	BAIAP3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA002547LC01HU	BAIAP3 Antibody, FITC conjugated
Biotin	CSB-PA002547LD01HU	BAIAP3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission.

Gene References into Functions

BAIAP3 functions indirectly in dense-core vesicle exocytosis by affecting DCV maturation through its role in DCV protein recycling. PMID: 28626000
Baiap3 is gender specifically associated with anxiety and benzodiazepine use disorder. PMID: 23698091

Subcellular Location

Cytoplasm, cytosol. Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.

Protein Families

Unc-13 family

Tissue Specificity

Predominantly expressed in brain. Also expressed in nonneural tissues such as breast and testes epithelium.

Database Links

HGNC: 948

OMIM: 604009

KEGG: hsa:8938

STRING: 9606.ENSP00000324510

UniGene: Hs.458427

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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