CAMK1D Antibody

Datasheet

Code	CSB-PA812863ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA812863ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA812863ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CAMK1D Polyclonal antibody

Uniprot No.

Q8IU85

Target Names

CAMK1D

Alternative Names

A630059D12Rik antibody; Calcium/calmodulin dependent protein kinase ID antibody; Calcium/calmodulin dependent protein kinase type 1D antibody; Calcium/calmodulin-dependent protein kinase I-delta antibody; Calcium/calmodulin-dependent protein kinase type 1D antibody; CaM K1 antibody; CaM KI delta antibody; CaM kinase I delta antibody; CaM kinase ID antibody; CaM-KI delta antibody; CAMK 1D antibody; CAMK1D antibody; CaMKI delta antibody; CamKI like protein kinase antibody; CamKI-like protein kinase antibody; CaMKID antibody; CKLiK antibody; E030025C11Rik antibody; KCC1D_HUMAN antibody; OTTHUMP00000019119 antibody; OTTHUMP00000019120 antibody; OTTHUMP00000045030 antibody; RP11 462F15.1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Calcium/calmodulin-dependent protein kinase type 1D protein (1-180AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.

Gene References into Functions

There were no statistically significant differences in the distribution of CDC123/CAMK1D rs12779790 genotypes and alleles between women with gestational diabetes mellitus and healthy pregnant women. PMID: 28079868
identified the CAMK1D gene as a novel locus associated with blood pressure response to losartan PMID: 25410890
Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDKN2A/2B), rs4402960 (IGF2BP2), rs12779790 (CDC123/CAMK1D), and rs2237892 (KCNQ1). PMID: 22923468
A significant association of rs10906115 in CDC123/CAMK1D and rs1359790 near SPRY2 was identified with type 2 diabetes in a Japanese population. PMID: 21909839
role of CKLiK in specific granulocyte effector functions such as phagocytosis, respiratory burst, migration, and adhesion PMID: 15840691
CAMK1D as a novel amplified oncogene linked to epithelial-mesenchymal transition in breast cancer, with elevated expression in invasive carcinomas compared to carcinoma in situ PMID: 19383354

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Subcellular Location

Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.

Protein Families

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily

Tissue Specificity

Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.

Database Links

HGNC: 19341

OMIM: 607957

KEGG: hsa:57118

STRING: 9606.ENSP00000368124

UniGene: Hs.600547

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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