CAMK2N2 Antibody

Code CSB-PA004470NA01HU
Size US$166
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  • Immunofluorescence staining of MCF-7 cells with CSB-PA004470NA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CAMK2N2 Polyclonal antibody
Uniprot No.
Target Names
CAMK2N2
Alternative Names
CAMK2N2Calcium/calmodulin-dependent protein kinase II inhibitor 2 antibody; CaM-KII inhibitory protein antibody; CaM-KIIN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 2 protein (10-28AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CAMK2N2 Antibody (Product code: CSB-PA004470NA01HU) is Non-conjugated. For CAMK2N2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA004470NB01HU CAMK2N2 Antibody, HRP conjugated ELISA
FITC CSB-PA004470NC01HU CAMK2N2 Antibody, FITC conjugated
Biotin CSB-PA004470ND01HU CAMK2N2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
Gene References into Functions
  1. Mutant FUS-DeltaNLS increased calcium/calmodulin-dependent protein kinase II inhibitor 2 (CAMK2N2) at both mRNA and protein levels. PMID: 23545117
  2. Murine double minute 2 (MDM2) protein levels were decreased in AD cells relative to control lymphoblasts, suggesting an impairment of FOXO3a degradation. PMID: 23153928
  3. We show that CaMKII N beta expression is differentially regulated by novelty and contextual fear conditioning, providing further insight into molecular basis of fear LTM. PMID: 20487031
  4. hCaMKIINbeta may play an important role in the regulation of tumor cell growth PMID: 19586909
  5. Functional study of the rat homolog PMID: 9724800

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Subcellular Location
Nucleus. Cytoplasm, cytosol.
Protein Families
CAMK2N family
Tissue Specificity
Expressed in cell lines including hemopoietic cell lines and some tumor cell lines. Highly Expressed in stimulated dendritic cell (DC) and weakly expressed in unstimulated mature and immature DC. Highly expressed in kidney, liver, in cell lines HeLaS3, ly
Database Links

HGNC: 24197

OMIM: 608721

KEGG: hsa:94032

STRING: 9606.ENSP00000296238

UniGene: Hs.585003

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