CBX4 Antibody, FITC conjugated

Datasheet
Code CSB-PA004600EC01HU
Size US$299
Uniprot No. O00257
Immunogen Recombinant Human E3 SUMO-protein ligase CBX4 protein (1-160AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2), CBX4
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Epigenetics and Nuclear Signaling
Target Names CBX4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I
Subcellular Location Nucleus, Nucleus speckle
Tissue Specificity Ubiquitous.
Database Links

HGNC: 1554

OMIM: 603079

KEGG: hsa:8535

STRING: 9606.ENSP00000269397

UniGene: Hs.405046

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