CD300LB Antibody

Datasheet

Code	CSB-PA004919LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CD300LB Polyclonal antibody

Uniprot No.

A8K4G0

Target Names

CD300LB

Alternative Names

CD300LB antibody; CD300B antibody; CLM7 antibody; CMRF35A2 antibody; IREM3 antibody; LMIR5 antibody; TREM5 antibody; UNQ2530/PRO6029CMRF35-like molecule 7 antibody; CLM-7 antibody; CD300 antigen-like family member B antibody; CMRF35-A2 antibody; Immune receptor expressed on myeloid cells 3 antibody; IREM-3 antibody; Leukocyte mono-Ig-like receptor 5 antibody; Triggering receptor expressed on myeloid cells 5 antibody; TREM-5 antibody; CD antigen CD300b antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human CMRF35-like molecule 7 protein (18-151AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CD300LB Antibody (Product code: CSB-PA004919LA01HU) is Non-conjugated. For CD300LB Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA004919LB01HU	CD300LB Antibody, HRP conjugated	ELISA
FITC	CSB-PA004919LC01HU	CD300LB Antibody, FITC conjugated
Biotin	CSB-PA004919LD01HU	CD300LB Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.

Gene References into Functions

this paper identified CD300b as an lipopolysaccharide-recognizing receptor that regulated TLR4 signaling PMID: 27261276
CD300LB expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo. PMID: 23072861
CD300b defines a nonclassical Ig receptor able to trigger signals by coupling distinct mediators and thus initiating different signaling pathways PMID: 16920917
although both mouse and human LMIR5 play activatory roles in innate immunity cells, the functions of LMIR5 were differentially regulated in mouse versus human cells. PMID: 17928527

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Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

CD300 family

Tissue Specificity

Expressed exclusively in myeloid lineages.

Database Links

HGNC: 30811

OMIM: 610705

KEGG: hsa:124599

STRING: 9606.ENSP00000376397

UniGene: Hs.313343

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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