CDK2AP2 Antibody

Code CSB-PA005063LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005063LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDK2AP2 Polyclonal antibody
Uniprot No.
Target Names
CDK2AP2
Alternative Names
CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CDK2AP2 Antibody (Product code: CSB-PA005063LA01HU) is Non-conjugated. For CDK2AP2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005063LB01HU CDK2AP2 Antibody, HRP conjugated ELISA
FITC CSB-PA005063LC01HU CDK2AP2 Antibody, FITC conjugated
Biotin CSB-PA005063LD01HU CDK2AP2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A.
Gene References into Functions
  1. Our findings suggest that alteration of p16, p14, p27, p21, and p53 status may contribute to carcinogenesis and the clinical behavior of HPV-negative adenocarcinoma of the uterine cervix PMID: 25675191
  2. antitumor effects of DOC-1R may be mediated by negatively regulating G1 phase progression and G1/S transition through inhibiting CDK2 expression and activation PMID: 23781148
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
CDK2AP family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 30833

KEGG: hsa:10263

STRING: 9606.ENSP00000301488

UniGene: Hs.523835

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