CGGBP1 Antibody

1. By studying global gene expression patterns and genome-wide DNA-binding patterns of CGGBP1, it has been shown that a possible mechanism through which it affects the expression of RNA Pol II-transcribed genes in trans depends on Alu RNA. PMID: 25483050
2. CGGBP1 has no direct effect on FMR1 transcription and CGG repeat stability. PMID: 26306647
3. CGGBP1 protein play an important cytoprotective role in patients with cancer. PMID: 26482656
4. CGGBP1 is a possible bidirectional regulator of CpG methylation at Alus, and acts as a repressor of methylation at L1 retrotransposons. PMID: 25981527
5. Our results suggest that CGGBP1 phosphorylation at S164 is a novel telomere protection signal, which can affect telomere-protective function of the shelterin complex PMID: 24196442
6. Over-expression of miR-7 could significantly inhibit the growth of human lung cancer cells in vivo and in vitro, which might be related to the down-regulated expression of tumor growth-associated protein CGGBP1 PMID: 24491049
7. CGGBP1 depletion by RNA interference in tumor-derived cells caused an increase in the cell population at G0/G1 phase and reduced the number of cells in the S phase. PMID: 21733196
8. CGGBP-20 downregulates the activity of 5'-region of FMR1 gene in the presence of GCC-triplets only. PMID: 20141036
9. CGGBP1 was mapped to chromosome 3p and a sequence of 235 nucleotides 5' upstream of CGGBP1 is essential for promoter activity. PMID: 14667814
10. Differences in factors implicated in CGG repeat instability--CGG repeat size, XS548/FRAXAC1 haplotypes, and AGG interspersion pattern-are present in the Basque populations analyzed. PMID: 19728537

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HGNC: 1888

OMIM: 603363

KEGG: hsa:8545

STRING: 9606.ENSP00000381428

UniGene: Hs.444818