CHAT Antibody

Datasheet
Code CSB-PA005314GA01HU
Product Type Purified Rabbit Anti Human PolyClonal Antibody
Size US$685
Uniprot No. P28329
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Immunogen Human CHAT
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB,IF
Storage Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity purified
Isotype IgG
Alias choline acetyltransferase;CHAT;CMS1A;CMS1A2 ;
Immunogen Species Homo sapiens (Human)
Target Names CHAT
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
HGNC 1912
RGD 1304627
MGI 88392
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Function Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
Involvement in disease Myasthenic syndrome, congenital, 6, presynaptic (CMS6)
Protein Families Carnitine/choline acetyltransferase family
Database Links

HGNC: 1912

OMIM: 118490

KEGG: hsa:1103

STRING: 9606.ENSP00000337103

UniGene: Hs.302002

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