CHIC2 Antibody

Code CSB-PA892453ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human bladder cancer using CSB-PA892453ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CHIC2 Polyclonal antibody
Uniprot No.
Target Names
CHIC2
Alternative Names
BrX-like translocated in leukemia antibody; BTL antibody; Chic2 antibody; CHIC2_HUMAN antibody; Cystein-rich hydrophobic domain 2 antibody; Cysteine-rich hydrophobic domain 2 protein antibody; MGC21173 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cysteine-rich hydrophobic domain-containing protein 2 protein (1-165AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. used fluorescence in situ hybridization to detect deletion of the CHIC2 locus at 4q12 as a surrogate for the FIP1L1-PDGFRA fusion and was observed in bone marrow cells for 3 of 5 patients with systemic mast cell disease associated with eosinophilia PMID: 12842979
  2. studied a new FISH method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocation in patients with myeloid neoplasms associated with eosinophilia PMID: 19118897
Involvement in disease
A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.
Subcellular Location
Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Protein Families
CHIC family
Database Links

HGNC: 1935

OMIM: 604332

KEGG: hsa:26511

STRING: 9606.ENSP00000263921

UniGene: Hs.335393

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