CHML Antibody

Code CSB-PA005357LA01HU
Size US$166
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  • Immunofluorescence staining of U251 cells with CSB-PA005357LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CHML Polyclonal antibody
Uniprot No.
Target Names
CHML
Alternative Names
CHM like antibody; Chml antibody; Choroideraemia like protein antibody; Choroideraemia-like protein antibody; Choroideremia like (Rab escort protein 2) antibody; Choroideremia like antibody; Choroideremia like protein antibody; Rab escort protein 2 antibody; Rab proteins geranylgeranyltransferase component A 2 antibody; RAE2_HUMAN antibody; REP 2 antibody; REP-2 antibody; REP2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Rab proteins geranylgeranyltransferase component A 2 protein (480-656AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CHML Antibody (Product code: CSB-PA005357LA01HU) is Non-conjugated. For CHML Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005357LB01HU CHML Antibody, HRP conjugated ELISA
FITC CSB-PA005357LC01HU CHML Antibody, FITC conjugated
Biotin CSB-PA005357LD01HU CHML Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Gene References into Functions
  1. Polymorphisms in the OPN3 and CHML genes are associated with asthma and atopic asthma. PMID: 18344558
Subcellular Location
Cytoplasm, cytosol.
Protein Families
Rab GDI family
Database Links

HGNC: 1941

OMIM: 118825

KEGG: hsa:1122

STRING: 9606.ENSP00000355511

UniGene: Hs.654545

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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