CINP Antibody

Code CSB-PA861151LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CINP Polyclonal antibody
Uniprot No.
Target Names
CINP
Alternative Names
CDK2-interacting protein antibody; CINP antibody; CINP protein antibody; CINP_HUMAN antibody; Cyclin dependent kinase 2 interacting protein antibody; Cyclin-dependent kinase 2-interacting protein antibody; MGC849 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cyclin-dependent kinase 2-interacting protein (1-212AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CINP Antibody (Product code: CSB-PA861151LA01HU) is Non-conjugated. For CINP Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA861151LB01HU CINP Antibody, HRP conjugated ELISA
FITC CSB-PA861151LC01HU CINP Antibody, FITC conjugated
Biotin CSB-PA861151LD01HU CINP Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
Gene References into Functions
  1. NS5B delays cells in S phase through interaction with CINP and relocalization of the protein from the nucleus to the cytoplasm PMID: 21628470
  2. CINP is part of the Cdc7-dependent mechanism of origin firing and a functional and physical link between Cdk2 and Cdc7 complexes at the origins PMID: 16082200
  3. CINP interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress, and G2 checkpoint integrity. PMID: 19889979
Subcellular Location
Nucleus. Note=Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
Protein Families
CINP family
Database Links

HGNC: 23789

OMIM: 613362

KEGG: hsa:51550

STRING: 9606.ENSP00000442057

UniGene: Hs.129634

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