CLEC2B Antibody

Code CSB-PA023160
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA023160(CLEC2B Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
CLEC2B
Alternative Names
CLEC2B antibody; AICL antibody; CLECSF2 antibody; IFNRG1C-type lectin domain family 2 member B antibody; Activation-induced C-type lectin antibody; C-type lectin superfamily member 2 antibody; IFN-alpha-2b-inducing-related protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human CLEC2B
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Review of C-type lectin-like receptor 2 and podoplanin interactions [review] PMID: 27960039
  2. Data suggest that vascular smooth muscle cells (VSMCs) stimulate platelets through platelet receptor CLEC-2, possibly leading to thrombus formation after plaque erosion. PMID: 26418160
  3. Lipid rafts do not directly contribute to CLEC-2 receptor activation in platelets. PMID: 25462818
  4. our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL axis. PMID: 23929856
  5. expressed in primary liver cancers PMID: 20663776
  6. NKp80 is expressed on a highly responsive subset of effector memory CD8 T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL-expressing cells. PMID: 18922855

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Subcellular Location
Membrane; Single-pass type II membrane protein.
Tissue Specificity
Expressed preferentially in lymphoid tissues, and in most hematopoietic cell types.
Database Links

HGNC: 2053

OMIM: 603242

KEGG: hsa:9976

STRING: 9606.ENSP00000228438

UniGene: Hs.85201

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