CLEC2B Antibody

Code CSB-PA272000
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA272000(CLEC2B Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
CLEC2B
Alternative Names
CLEC2B antibody; AICL antibody; CLECSF2 antibody; IFNRG1C-type lectin domain family 2 member B antibody; Activation-induced C-type lectin antibody; C-type lectin superfamily member 2 antibody; IFN-alpha-2b-inducing-related protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human CLEC2B
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. Review of C-type lectin-like receptor 2 and podoplanin interactions [review] PMID: 27960039
  2. Data suggest that vascular smooth muscle cells (VSMCs) stimulate platelets through platelet receptor CLEC-2, possibly leading to thrombus formation after plaque erosion. PMID: 26418160
  3. Lipid rafts do not directly contribute to CLEC-2 receptor activation in platelets. PMID: 25462818
  4. our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL axis. PMID: 23929856
  5. expressed in primary liver cancers PMID: 20663776
  6. NKp80 is expressed on a highly responsive subset of effector memory CD8 T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL-expressing cells. PMID: 18922855

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Subcellular Location
Membrane; Single-pass type II membrane protein.
Tissue Specificity
Expressed preferentially in lymphoid tissues, and in most hematopoietic cell types.
Database Links

HGNC: 2053

OMIM: 603242

KEGG: hsa:9976

STRING: 9606.ENSP00000228438

UniGene: Hs.85201

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