CLSTN2 Antibody

Code CSB-PA863978LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA863978LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA863978LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CLSTN2 Polyclonal antibody
Uniprot No.
Target Names
CLSTN2
Alternative Names
CLSTN2 antibody; CS2Calsyntenin-2 antibody; Alcadein-gamma antibody; Alc-gamma antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Calsyntenin-2 protein (473-673AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CLSTN2 Antibody (Product code: CSB-PA863978LA01HU) is Non-conjugated. For CLSTN2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA863978LB01HU CLSTN2 Antibody, HRP conjugated ELISA
FITC CSB-PA863978LC01HU CLSTN2 Antibody, FITC conjugated
Biotin CSB-PA863978LD01HU CLSTN2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
May modulate calcium-mediated postsynaptic signals.
Gene References into Functions
  1. Study did not find support for an association of KIBRA either alone or in combination with CLSTN2 with memory performance or hippocampal volume, nor did variation in these genes influence longitudinal memory decline or hippocampal atrophy in older adults PMID: 26415670
  2. The results of this study supports the view that effects of KIBRA and CLSTN2 polymorphisms genetic polymorphisms on cognitive functioning may be most easily disclosed at suboptimal levels of cognitive ability, such as in old-age depression. PMID: 25080189
  3. No increased risk of any type of late development, and cognitive impairment was associated with CLSTN2 (rs6439886) PMID: 21643791
  4. This study showed that the KIBRA and CLSTN2 genes interactively modulate episodic memory performance. PMID: 19804789
  5. Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation [alcalpha1, alcbeta, alcgamma] PMID: 15037614
  6. calsyntenins play an essential role in learning and this role is modulated both by CLSTN2 genotype and, during adolescent development, by exposure to tobacco smoke. PMID: 19058786

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Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell junction, synapse, postsynapse. Cell projection, dendrite.
Tissue Specificity
Restricted to the brain.
Database Links

HGNC: 17448

OMIM: 611323

KEGG: hsa:64084

STRING: 9606.ENSP00000402460

UniGene: Hs.158529

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