CMIP Antibody

1. Genome-wide significant (P < 5 x 10(-8) ) interaction with MTNR1B and joint effects were detected for CMIP intronic rs17197883. PMID: 29691896
2. each copy of CMIP rs2925979_T allele was associated with a 29% higher risk of T2DM in females (p = 9.30 x 10(-4)), while it was not significantly associated with T2DM in males (p = 0.705). PMID: 29597287
3. CMIP knockdown was observed to result in the downregulation of MDM2 and mitogen activated protein kinase (MAPK) expression at the mRNA level and CMIP was a direct target of miR1013p. PMID: 28944848
4. CMIP is oncogenic and could be a potential target for human glioma diagnosis and therapy. PMID: 28744466
5. These findings suggest that CMIP haploinsufficiency is the likely cause of syndromic Autism spectrum disorder in our patients. PMID: 28504353
6. Wilm's tumor protein (WT1) bound to 2 WT1 response elements, located at positions -290/-274 and -57/-41 relative to transcription start site. PMID: 27650733
7. Results suggest that c-mip and RelA define two distinct types of renal damage associated with VEGF-targeted therapies. PMID: 24067439
8. c-mip has an active role in the podocyte disorders of membranous nephropathy. PMID: 23302718
9. These results suggest that alterations in NF-kappaB activity might result from the up-regulation of c-mip and are likely to contribute to podocyte disorders in cases of idiopathic nephrotic syndrome. PMID: 22507836
10. we provide novel evidence that the language-disorder candidate gene CMIP is implicated in reading processes. PMID: 21457949
11. Eight suggestive significant loci were detected with a series of genes expressed within the inner ear that underlie the auditory function, such as: DCLK1, PTPRD, GRM8, CMIP. PMID: 21493956
12. results identify c-mip as a key component in the molecular pathogenesis of acquired podocyte diseases PMID: 20484117
13. Induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes is associated with minimal change nephrotic syndrome in classical Hodgkin lymphoma. PMID: 20200355
14. results suggest that Tc-mip plays a critical role in Th2 signaling pathway and represents the first proximal signaling protein which links TCR-mediated signal to the activation of c-maf Th2 specific factor PMID: 12939343
15. Filamin-A interacts with c-mip/Tc-mip in a new T-cell signaling pathway. PMID: 15128042
16. c-mip inhibits the degradation of I-kappaBalpha and impedes the dissociation of the NF-kappaB/I-kappaBalpha complexes. PMID: 19019440
17. CMIP modulates phonological short-term memory in language impairment. PMID: 19646677

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HGNC: 24319

OMIM: 610112

KEGG: hsa:80790

STRING: 9606.ENSP00000446100

UniGene: Hs.594095