CMTM1 Antibody

Code CSB-PA006820
Size US$100
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Product Details

Uniprot No.
Target Names
CMTM1
Alternative Names
CMTM1; CKLFSF1; CKLF-like MARVEL transmembrane domain-containing protein 1; Chemokine-like factor superfamily member 1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human CMTM1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IF, ELISA
Recommended Dilution
Application Recommended Dilution
IF 1:200-1:1000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. High CMTM1_v17 expression was associated with chemotherapy resistance in lung cancer. PMID: 28129775
  2. CMTM1 and 3 are priority targets in glioblastomas. First insights into signalling of these two genes that might be conveyed by growth factor receptor, Src family kinase and WNT activation was presented. PMID: 25931111
  3. Study shows that CMTM1_v17 is highly expressed in human testis and many human tumor tissues and cell lines and seems to enhance cell proliferation and resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in MDA-MB-231 breast cancer cells. PMID: 25175386
  4. gene structure, mapping to chromsome 16, identification of altenative transcription start sites, expression in spermatocyte and testes PMID: 15147728
  5. novel evidence that the final intron/exon region of the CKLFSF1 gene contains a novel eukaryotic promoter capable of directing expression of the downstream gene, CKLFSF2 PMID: 15778092

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Chemokine-like factor family
Tissue Specificity
Highly expressed in testis.
Database Links

HGNC: 19172

OMIM: 607884

KEGG: hsa:113540

STRING: 9606.ENSP00000368814

UniGene: Hs.15159

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