CNOT10 Antibody

Code CSB-PA884495LA01HU
Size US$166
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Image
  • IHC image of CSB-PA884495LA01HU diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CNOT10 Polyclonal antibody
Uniprot No.
Target Names
CNOT10
Alternative Names
CNOT10CCR4-NOT transcription complex subunit 10 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human CCR4-NOT transcription complex subunit 10 protein (595-744AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CNOT10 Antibody (Product code: CSB-PA884495LA01HU) is Non-conjugated. For CNOT10 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA884495LB01HU CNOT10 Antibody, HRP conjugated ELISA
FITC CSB-PA884495LC01HU CNOT10 Antibody, FITC conjugated
Biotin CSB-PA884495LD01HU CNOT10 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.
Gene References into Functions
  1. Human CNOT10 and CNOT11 form a complex that interacts with the CNOT1 N-terminal domain. PMID: 23303381
  2. CNOT11 interacts with the first amino acids of CNOT1 and with CNOT10 and is required for the association of CNOT10 with the CCR4-NOT complex. PMID: 23232451
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
CNOT10 family
Database Links

HGNC: 23817

KEGG: hsa:25904

STRING: 9606.ENSP00000330060

UniGene: Hs.444851

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