COG1 Antibody

Code CSB-PA783442
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA783442(COG1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA783442(COG1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
COG1
Alternative Names
COG1 antibody; KIAA1381 antibody; LDLBConserved oligomeric Golgi complex subunit 1 antibody; COG complex subunit 1 antibody; Component of oligomeric Golgi complex 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human COG1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for normal Golgi function.
Gene References into Functions
  1. This study reports a novel set of Dengue virus (DENV) NS1-interacting host cell proteins in the HepG2 cell line and proposes possible roles for human NEK2, TAO1, and COG1 in DENV infection. PMID: 27108190
  2. Chronic renal patients with more atherogenic lipoprotein LDL B phenotype are in advanced state of oxidative stress compared with control subjects. PMID: 27412679
  3. Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp PMID: 11929878
  4. These findings support the proposal that COG is directly involved in controlling vesicular retrograde transport of Golgi resident proteins throughout the Golgi apparatus. PMID: 16857184
  5. A novel mutation in COG1 was found in two patients with a cerebrocostomandibular-like syndrome. PMID: 19008299

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Involvement in disease
Congenital disorder of glycosylation 2G (CDG2G)
Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
COG1 family
Database Links

HGNC: 6545

OMIM: 606973

KEGG: hsa:9382

STRING: 9606.ENSP00000299886

UniGene: Hs.103555

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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