COG8 Antibody

Datasheet

Code	CSB-PA846673LA01HU
Size	US$166
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Image	IHC image of CSB-PA846673LA01HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) COG8 Polyclonal antibody

Uniprot No.

Q96MW5

Target Names

COG8

Alternative Names

COG8 antibody; Conserved oligomeric Golgi complex subunit 8 antibody; COG complex subunit 8 antibody; Component of oligomeric Golgi complex 8 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Conserved oligomeric Golgi complex subunit 8 protein (521-612AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The COG8 Antibody (Product code: CSB-PA846673LA01HU) is Non-conjugated. For COG8 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA846673LB01HU	COG8 Antibody, HRP conjugated	ELISA
FITC	CSB-PA846673LC01HU	COG8 Antibody, FITC conjugated
Biotin	CSB-PA846673LD01HU	COG8 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Required for normal Golgi function.

Gene References into Functions

The exome sequencing was performed to screen all CDG type II-related genes, and two novel frameshift mutations were found: c.171dupG (p.Leu58Alafs*29) and c.1656dupC (p.Ala553Argfs*15) in COG8. PMID: 28619360
TMED6-COG8 chimera might act as a novel diagnostic marker in TFE3 translocation renal cell carcinoma. PMID: 26045774
wthe origin, evolution and preservation of the COG8/PDF same-strand overlap follow similar mechanistic steps as those documented for antisense overlaps where gain and/or loss of splice sites and polyadenylation signals seems to drive the process. PMID: 21805148

Involvement in disease

Congenital disorder of glycosylation 2H (CDG2H)

Subcellular Location

Golgi apparatus membrane; Peripheral membrane protein.

Protein Families

COG8 family

Database Links

HGNC: 18623

OMIM: 606979

KEGG: hsa:84342

STRING: 9606.ENSP00000305459

UniGene: Hs.130849

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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