COL19A1 Antibody

Code CSB-PA213241
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue using Collagen XIX α1 antibody.
  • Immunofluorescence analysis of A549 cells, using Collagen XIX α1 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) COL19A1 Polyclonal antibody
Uniprot No.
Target Names
COL19A1
Alternative Names
COJA1_HUMAN antibody; COL19A1 antibody; COL9A1L antibody; Collagen alpha-1(XIX) chain antibody; Collagen alpha-1(Y) chain antibody; D6S228E antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human Collagen XIX α1.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC,IF
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.
Gene References into Functions
  1. Naturally occurring interruptions in nonfibrillar collagen play key roles in molecular flexibility, collagen degradation, and ligand binding. This study focused on a G5G type natural interruption sequence G-POALO-G from human type XIX collagen, a homotrimer collagen, as this sequence possesses distinct properties compared with those of a pathological similar Gly mutation sequence in collagen mimic peptides. PMID: 29376320
  2. Type XIX collagen is a new partner in the interactions between tumor cells and their microenvironment. (Review) PMID: 27491275
  3. collagen IX has unique cell adhesion properties when compared with other collagens, and it provides a novel mechanism for cell adhesion to cartilaginous matrix PMID: 15383545
  4. The NC2 domain of collagen XIX and probably of other FACITs is responsible for chain selection and trimerization PMID: 18845531
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Fibril-associated collagens with interrupted helices (FACIT) family
Tissue Specificity
Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.
Database Links

HGNC: 2196

OMIM: 120165

KEGG: hsa:1310

STRING: 9606.ENSP00000316030

UniGene: Hs.444842

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