CPPED1 Antibody

Datasheet
Code CSB-PA871558LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q9BRF8
Image
  • IHC image of CSB-PA871558LA01HU diluted at 1:400 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Serine/threonine-protein phosphatase CPPED1 protein (49-186AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:200-1:500
Relevance Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1), CPPED1, CSTP1
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names CPPED1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Subcellular Location Cytoplasm
Protein Families Metallophosphoesterase superfamily, CPPED1 family
Tissue Specificity Expressed in subcutaneous adipose tissue.
Database Links

HGNC: 25632

OMIM: 615603

KEGG: hsa:55313

STRING: 9606.ENSP00000371193

UniGene: Hs.460002

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